Woodruff Well being Sciences Middle |
June 8, 2021
The Emory neighborhood is mourning the passing of Stephen T. Warren, the founding and former chair of the College of Drugs’s Division of Human Genetics. Warren died peacefully at his residence in Atlanta on June 6. He was 67.
Tributes to Warren poured in by way of social media from numerous corners of the world, lauding him for his analysis management and his unbelievable contributions to the world’s understanding of fragile X syndrome, a number one reason behind inherited mental incapacity and autism.
Warren was the previous Charles Howard Candler Chair of Human Genetics and the William Patterson Timmie Professor of Human Genetics at Emory. He joined the College of Drugs as an assistant professor in 1985 within the Departments of Biochemistry and Pediatrics (medical genetics) and was promoted to affiliate professor in 1991 and full professor in 1993. In 2020, Warren stepped down as division chair after 35 years of service to Emory.
Warren’s analysis at Emory targeted on the mechanistic understanding of fragile X syndrome. In 1991, he led a global effort that recognized the gene mutation chargeable for the syndrome, which paved the way in which for therapies.
Warren then found the educational and reminiscence protein whose manufacturing is affected by the mutated gene. That discovery allowed him to develop the primary diagnostic take a look at for fragile X. He additionally led medical trials for the event of medicine to deal with the situation. Lately, he and his collaborators initiated a undertaking to determine the genetic origins that predispose some people to schizophrenia.
“Dr. Warren was a exceptional scientist and human being,” says Jan Love, Emory’s interim provost and govt vice chairman for educational affairs, extending her deepest condolences to his household. “His analysis remodeled the lives of sufferers and households grappling with fragile X syndrome. His passing is a large loss for the Emory neighborhood and past.”
College of Drugs Dean Vikas Sukhatme remembers his first impressions of Warren vividly. “I had the pleasure of figuring out Dr. Warren for just a few years, however was instantly struck by how gifted a scientist, chief, mentor and pal he was,” Sukhatme says. “He inspired me to suppose boldly for the Emory College of Drugs. We owe him a long-lasting debt for his immense contributions to the college and to science broadly. We’ll miss him.”
Inspirational researcher, mentor and pal
Whereas in school, Warren joined the American Society of Human Genetics and served the society in lots of capacities over his 50-year-long profession, together with because the president of the society in 2006. In 1999, he received the William Allan Award, the society’s highest honor. In 2003, Warren was an inaugural inductee of the Nationwide Institute of Baby Well being and Human Improvement’s Corridor of Honor for the “identification of triplet repeat enlargement as the reason for fragile X syndrome and as a completely new inherited mechanism of genetic illness.”
In 2011, Warren acquired the March of Dimes/Colonel Harland Sanders Award for lifetime achievement. Warren was elected to the Nationwide Academy of Drugs in 2004, the Nationwide Academy of Sciences in 2011 and the American Academy of Arts and Sciences in 2015. He was a diplomat of the American Board of Medical Genetics and the previous Editor-in-Chief of the American Journal of Human Genetics.
Other than his analysis contributions, Warren was additionally identified for his generosity and dedication to nurturing the following era of scientists; quite a few postdoctoral fellows in addition to graduate and undergraduate college students at Emory and past benefitted from his counsel, steering and mentorship.
Emory professor Peng Jin, who succeeded Warren as chair of the Division of Human Genetics, known as him an inspirational determine for him and others at Emory.
“I had the privilege and honor of working with Steve for the previous 22 years. Steve was an unbelievable mentor, colleague, collaborator and fantastic pal. He’s a sport changer in human genetics and his work has impressed so many scientists and impacted so many households,” Jin says.
“Steve was at all times considerate, devoted and unstintingly beneficiant together with his time, his huge mind and his impeccable judgment,” he continues. “He introduced worldwide recognition and prominence in genetics to Emory. The Division of Human Genetics is a part of his legacy that we are going to keep on. His passing is an unbelievable loss, and we are going to miss him dearly.”
Jeremy Boss, professor and chair of the College of Drugs’s Division of Microbiology and Immunology, was Warren’s shut pal and colleague for greater than 30 years. “I had the privilege of sharing many moments with him,” Boss remembers. “As a younger school member, Steve had a transparent imaginative and prescient of what he wished to perform as a scientist, a frontrunner and a mentor.
“Foremost on his listing was to make a distinction within the area, and we all know that he did so in spectacular methods. His science was actually on the apex of human genetics and plenty of sufferers benefited from his discoveries,” he notes. “Steve additionally had eager perception into how organizations ought to work and was capable of create a world class division and put it into place and take kind. His phrases of council and mentorship have been at all times significant and considerate. I’ll miss him and can cherish recollections of our instances collectively.”
Born in 1953 in East Detroit, Michigan, Warren was an solely baby whose dentist father sparked an early curiosity in science. He started his undergraduate research at Michigan State College and graduated with a BS in zoology and continued there to get his doctoral diploma in human genetics. Warren accomplished his submit graduate coaching on the College of Illinois at Chicago at its Middle for Genetics and on the European Molecular Biology Laboratory at its principal web site in Heidelberg, Germany. He joined the Howard Hughes Medical Institute as an investigator in 1991. He left that place in 2002 to function the founding chair of the Division of Human Genetics at Emory’s College of Drugs.
Warren is survived by his spouse, Dr. Karen Warren; his son, Thomas Warren; and his son’s fiancée, Desiree Chand.
In lieu of flowers, the household asks that donations in Warren’s honor be despatched to FRAXA, a basis devoted to analysis on fragile X.
Memorial providers will probably be held at a date but to be introduced.