Scientific trial outcomes have proven that this molecule helps in sooner restoration of hospitalised sufferers and reduces supplemental oxygen dependence.
Larger proportion of sufferers handled with 2-DG confirmed RT-PCR unfavourable conversion in COVID sufferers.
In response to the EoI doc, purposes needs to be submitted earlier than June 17 via e-mail.
“The EoI submitted by industries will probably be scrutinised by a Technical Evaluation Committee (TAC).
Solely as much as 15 industries will probably be given ToT on their capabilities, technical hand holding functionality of DRDO and on First Come First Served Foundation,” it mentioned.
The bidders ought to have a Drug license to fabricate Lively Pharmaceutical Ingredient (API) from Drug Licensing Authorities and WHO GMP (Good manufacturing Practices) certification amongst others.
Laboratory synthesis course of for 2-DG has been developed utilizing D-Glucose as beginning materials.
The synthesis course of consists of conversion of D-Glucose to 2-DG via 5 chemical response steps adopted by purification.
The method has been established at batch scale (100g) and pilot plant scale (500g) and vital patents have been filed by DRDO on this regard, the Defence physique mentioned.